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Avandia (Rosiglitazone)

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Avandia (Rosiglitazone) is applied in cases of type II diabetes for helping to control blood glucose concentration.

Drug Name
Trade Mark Name: Avandia
Generic Name: Rosiglitazone

Drug Uses
Avandia is an effective medication used for treatment of type II diabetes as a part of treatment schedule that includes keeping to a special diet for patients with diabetes, weight control methods, doing regular physical exercises, restricting patient in smoking and accurate control of blood glucose level. Avandia falls into the group of anti-diabetes medicines called glitazones, also known as thiazolidinedione-type drugs. Another effective anti-diabetes drug of this pharmacological group is Actos (Pioglitazone). It is recommended to use Avandia alongside with some drugs of other anti-diabetes class like metformins to achive better results in lowering blood glucose. Avandia can be safely used in combination with other well-established anti-diabetes drugs like insulin and sulfonylureas. COntrolling blood glucose concentration is crucial in patients with diabetes as the failure to timely normalize the level of sugar in blood may result in acquiring severe heart irregularities, including strokes and seizures, kidney injures, loss of the sight, and blood circulation problems, including male erectile dysfunction (impotence).

How Taken
The usual dose of Avandia is made up by one or two tablets per day. The dose may vary according to your doctor's prescription. Avandia can be taken both with and without food. The exact dosage is conditioned solely by your medical state, sensitivity to the drug components and the general consistency of your therapy. Avandia must be taken on a regular basis for it to produce the expected effect. In order to forget missing doses take your medications about the same time each day. Keep all your clinic and laboratory appointments accurate to monitor the level of your blood sugar and the progress in your medical condition. Keep in mind that Avandia may start producing its optimal effect in 2 or 3 months, therefore it is crucial to follow all of your doctor's prescriptions with accuracy to get the full benefit of the medication.

Drug Class and Mechanism
Avandia works by lowering glucose, or sugar, level in the blood by way of reducing of glucose production by liver. Taking Actos on a regular basis helps to reduce the level of lipids which are otherwise known as fats in the blood thus lowering triglycerides and increasing the HDL cholesterol production.Avandia is an oral medication that helps patients with type II diabetes (non insulin-dependant patients) to release adequate quantity of insulin for proper stimulation of the blood cells that helps the organism to dispose of the excess glucose. Insulin is a protein hormone, secreted in the pancreas by the islets of Langerhans, that controls the concentration of glucose in the blood. Insulin deficiency results in diabetes mellitus. Drugs like Avandia do not directly supply the organism of the patient with insulin, but makes the blood cells more sensitive to the effects of insulin by way of stimulating insulin receptors, that is why Avandia is commonly referred to as "insulin synthesizer". Therefore the principal condition of using Avandia is that the organism of the patient produces at least some quantity of insulin for the drug to be effective.

Missed Dose
If you are taking Avandia regularly and happen to miss a dose, take one as soon as you remember to. if you remembered about the missed dose too late, that is before the actual taking of the next scheduled dose, do not catch up with the dosing schedule taking two doses at once.

Storage
Avandia should be kept in a dry place at temperature ranging from 15 to 30 degrees C (from 59 to 86 degrees F) away from the sources of heat and light. Keep the medication out of the reach of children and domestic animals.

Warnings/Precautions
Notify our doctor about any possible allergic symptoms you may develop while taking Avandia basing on the information of your previous allergic reactions towards medications of glitazone group, including pioglitazone and troglitazone and other medical intolerances, if any. Avandia is not recommended for the use in patients with certain medical conditions, including type I diabetes (insulin-dependent diabetes), excretion of an abnormally large amount of urine (diabetic ketoacidosis), newly acquired or aggravating heart irregularities, progressing liver disorders. Check with your doctor the appropriateness of Avandia therapy by discussing the details of your medical history, especially of your heart and liver condition, fluid in lungs, excessive accumulation of serous fluid in the intercellular spaces of tissue (oedema), a deficiency in the number of red blood cells or in their haemoglobin content, resulting in pallor, shortness of breath, and lack of energy (anaemia), atherosclerosis.
Patients taking Avandia as well as other anti-diabetes medications absolutely must not break their dosing schedule before consulting their doctor. 
 
Please ask your doctor’s advice in case you are planning to reduce, increase or in any other way change your regular Avandia dosing schedule. 
 
You can be under the risk of getting hypoglycemic reactions connected with low glucose indexes if you are taking Avandia alongside with some other anti-diabetes medications. Check the possibilities of avoiding adverse side effects with your doctor or any other health care provider.
Patients who are using Avandia to lower glucose in the blood should attend their doctor or any other health care provider regularly to take all the necessary tests that will help keep the situation under control in terms of the progress made in the course of treatment and helping them to avoid adverse side effects.  
In any case of medical interference patients taking Avandia should inform the responsible health care specialist about this fact, be it a dentist or a surgeon. 
Ask your doctor if you are going to take some other medicines alongside with taking Avandia as there may be undesirable reciprocal interference between the two medicines. This also concerns birth control pills and other oral contraceptives. If you are taking any such pills, keep in mind that Avandia can lower the efficiency of oral contraceptives by renewing ovulation in premenopausal period, therefore use additional barrier birth control means to prevent undesirable pregnancy.
Women who are planning to conceive should consult their doctor as for the possibilities of going on with taking Avandia. Women who are currently breast-feeding must not take Avandia during lactation period as the medication is easily absorbed by the breast milk.  Taking Avandia may result in irregular menstrual flow and certain fertility problems. Consult your doctor on these points.

Possible Side Effects
The list of the most probable side effects traced with the patients taking Avandia includes such symptoms as headaches, pain in muscles, toothaches, hypoglycemia (low blood glucose), various kinds of sinusitis, infections of the upper respiratory tract and throat inflammations. Carry some source of quick glucose with you in case you start developing hypoglycemia symptoms like headache, dizziness, nausea (non-dietic soda, sweets) or some reliable sources of sugar like glucose-rising medications.
Another side effect that may be caused by Avandia is oedema, or fluid accumulation, which in its turn may lead to severe heart irregularities. This effect may be increased if the patient is currently taking other anti-diabetes medications as has been proved in the course of the research. 
As for the interaction of Avandia with other drugs, there has been no evidence so far that the tablets can come into reactions with other medications. However, patients taking Avandia should be particularly careful while taking such medications as erythromycin, trimetrexate, cisapride (Propulsid), triazolam (e.g., Halcion), trimetrexate, calcium channel blockers like Cardizem, corticosteroids, Lipitor and other HMG-CoA reductase inhibitors as Avandia can decrease their efficiency by interacting with liver enzymes. 
As there has been a precedent with another thiazolidinedione medication used for treating diabetes it is recommended that patients who are currently taking Actos be subjected to accurate monitoring which will enable their doctors to control liver state in order to avoid severe injuries. The symptoms of such liver injuries may include acute abdominal pain, tiredness, dramatic loss of appetite (anorexia), nausea, vomiting, and dark urine. Ask your doctor to prescribe you blood liver tests while taking Avandia.

 
More Information
Keep up with the physical exercises schedule advised by your doctor or any other health care provider as well as the special anti-diabetes diet prescribed for you while undergoing Avandia therapy. Keep your diabetes identification card with you all the time. Get your blood glucose monitored as prescribed by your doctor on a regular basis. If you notice some deviations from the norm in your glucose level tests results seek immediate attention of your doctor.

Avandia is not meant for the use of people to whom it has not been prescribed and those who are suffering from other health problems. Do not fail to renew your supply of Avandia before you run out of it in order not to break your regular dosing schedule. 

Do I need a prescription to buy Avandia (Rosiglitazone) in your online drug store?
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