Baclofen Tablets

Baclofen
4.86 ratingsReviews
Generic:
Baclofen
Indications:
spasms
Analogs:
Tizanidine Dantrolene Diazepam Botulinum Toxin Type A Lioresal Gablofen Ozobax Lyvispah Sirdalud Dantrium Valium Cyclobenzaprine Methocarbamol Tolperisone
We stock oral Baclofen tablets in 10 mg and 25 mg strengths, a centrally acting muscle relaxant used for spasticity, with 10 mg packs of 60 to 360 pills and 25 mg packs of 30 to 270 pills.
In stock: 22 packs
AdultsPregnancyAllergiesDiabetesBreastfeedingChildrenDriving

Dosages

Baclofen 10 mg

Quantity Price per tablet You save Total price
60 $0.88 - $52.60
90 $0.76 $10.80 $68.10
120 $0.72 $19.10 $86.10
180 $0.66 $39.30 $118.50
270 $0.63 $66.30 $170.40
360 $0.61 $95.30 $220.30

Baclofen 25 mg

Quantity Price per tablet You save Total price
30 $2.80 - $83.90
60 $2.06 $44.50 $123.30
90 $1.80 $89.30 $162.40
120 $1.70 $132.00 $203.60
180 $1.58 $219.20 $284.20
270 $1.51 $348.70 $406.40

Manufacturers

Aliud PharmaAlphapharmApotexLaboratoires EthypharmNovartis FarmacéuticaNovartis Farma S.p.A.Novartis PharmaNovartis PharmaceuticalsNovartis Pharmaceuticals CanadaNovartis Pharmaceuticals UKNovartis Pharma GmbHratiopharmTeva CanadaZentiva France

Payment & Shipping

A Standard Package

We carefully pack each order and ship it within 24 hours. Below is an example of a standard package.

The packaging measures 9.4x4.3x0.3 inches (24x11x0.7 cm), similar to a standard personal envelope, and conceals its contents.

Front View
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Back View
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Shipping Times
Shipping MethodEstimated delivery
Express Free for orders over $300.00Estimated delivery to the U.S.: 4-7 days
Standard Free for orders over $200.00Estimated delivery to the U.S.: 14-21 days
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Discount Coupons

  • Independence Day - July 4, 2026 10% JULY410
  • Labor Day - September 7, 2026 7% LABOR07
  • Thanksgiving - November 26, 2026 9% THANKS09

FAQ

Inactive ingredients can vary among manufacturers and formulations. Check the supplied package information or ask a pharmacist before use if you need to avoid a specific excipient.

Take these tablets by mouth exactly as prescribed, preferably with food or milk if stomach irritation occurs. Baclofen is commonly started at a low dose and increased gradually when needed; do not stop it suddenly, because withdrawal symptoms can occur.

Description

If you are weighing Baclofen tablets against another muscle relaxant, the first thing worth knowing is what we actually sell: immediate-release oral tablets in 10 mg and 25 mg strengths, not an extended-release capsule, oral solution, or injectable formulation sold under other brand names. That distinction matters because dosing frequency, onset, and how a prescriber titrates the medication all depend on the exact form in your hand. Everything in this guide describes the tablets we offer, so you can compare them accurately against other options before deciding.

Baclofen is a well-established skeletal muscle relaxant, classified under ATC code M03BX01, used to reduce spasticity, the involuntary muscle tightness, spasm, and stiffness that can follow conditions affecting the central nervous system. It works differently from many other muscle relaxants on the market, which is one of the reasons prescribers choose it for specific patients rather than as a universal substitute.

Baclofen Tablets: Identity and Role

Our current offer is Baclofen oral tablets, taken by mouth, supplied in 10 mg and 25 mg strengths. Baclofen belongs to the skeletal muscle relaxant class and is chemically related to gamma-aminobutyric acid (GABA), the body's main inhibitory neurotransmitter. Clinically, it is recognized for easing the signs and symptoms of spasticity resulting from multiple sclerosis and spinal cord injury in adults, where it can reduce painful spasms, clonus, and muscle rigidity that interfere with movement, positioning, or daily care.

Unlike a combination product, Baclofen tablets contain a single active ingredient, which keeps dosing straightforward and makes it easier for a prescriber to adjust the amount without juggling multiple compounds. Our 10 mg and 25 mg strengths allow a clinician to fine-tune a regimen as it is increased from a low starting dose toward an effective maintenance level.

Who May Consider Baclofen?

Baclofen tablets are established for adults with spasticity linked to multiple sclerosis or spinal cord injury, and the same active ingredient is used in adolescents 12 years and older, though pediatric dosing is individualized and started low. It is not established as safe and effective in children under 12. Beyond age, a few practical factors typically shape whether Baclofen is a reasonable fit:

  • Spasticity that affects mobility, sleep, positioning, or the ability to tolerate physical therapy.
  • A preference for a centrally acting oral option over an injectable or peripherally acting alternative.
  • No known hypersensitivity to baclofen or any tablet ingredient.
  • Willingness to follow a gradual titration and to avoid stopping the medication abruptly.
  • An openness to discuss pregnancy, breastfeeding, or existing conditions like diabetes with a healthcare provider before starting.

People managing other forms of muscle tightness, such as ordinary short-term muscle strain, are generally treated with different medications, since Baclofen's established role centers on spasticity of central nervous system origin rather than everyday musculoskeletal pain.

How Does Baclofen Work, and What Does That Mean in Practice?

Baclofen acts primarily at the spinal cord level, where it stimulates GABA-B receptors. This inhibits the transmission of excitatory signals between nerve cells that would otherwise trigger exaggerated muscle reflexes. In practical terms, that means Baclofen does not act directly on the muscle fibers themselves; instead, it dampens the nerve signaling that causes muscles to stay contracted or to spasm repeatedly.

For someone living with spasticity, this typically translates into fewer spasm episodes, reduced muscle tone at rest, and, for many, an easier time with stretching, transfers, hygiene care, or physical therapy exercises. Because the effect is centrally mediated, sedation and drowsiness are common accompanying effects, which is worth factoring into any daily routine, especially around driving or tasks requiring alertness.

How to Use Baclofen and Build a Routine

Baclofen is generally started at a low dose and increased gradually under a prescriber's direction, a process called titration, until the lowest dose that controls symptoms with tolerable side effects is reached. Because the tablets have a relatively short duration of action, most regimens involve multiple doses spread across the day rather than a single daily dose.

Building a Consistent Schedule

Taking each dose at roughly the same times daily helps maintain steadier symptom control and reduces the chance of missed doses. Baclofen can be taken with or without food; taking it with a meal or snack may help if it causes stomach upset.

Practical Tips for Staying on Track

  • Keep doses evenly spaced through the day rather than clustering them together.
  • Do not stop Baclofen suddenly after regular use; abrupt discontinuation has been associated with withdrawal effects, including hallucinations, agitation, and seizures, so any dose reduction should be planned with a healthcare provider.
  • Store tablets at 68°F to 77°F, with brief excursions permitted between 59°F and 86°F, in a tightly closed, light-resistant container away from moisture.
  • If a dose is missed and it is close to the next scheduled dose, do not double up; resume the normal schedule.

Our Available Strengths and Package Sizes

We list Baclofen tablets in two strengths, each with its own range of package sizes measured in pills, so the quantity can be matched to how a prescriber has structured the regimen:

  • 10 mg tablets: available in packs of 60, 90, 120, 180, 270, or 360 pills.
  • 25 mg tablets: available in packs of 30, 60, 90, 120, 180, or 270 pills.

Because titration often starts at a lower total daily dose and increases over time, some customers begin with a smaller 10 mg package and move toward the 25 mg strength, or a larger pack size, as their prescriber adjusts the regimen. Reviewing the exact strength and pack size against the prescribed regimen before ordering helps avoid mismatched quantities.

What Results Can You Expect, and When?

Some reduction in spasm frequency or muscle tightness can appear within the first days of treatment, but the fuller benefit of Baclofen typically develops over several weeks as the dose is titrated upward to an effective, tolerated level. Because each tablet has a relatively short duration of action, symptom control tends to track closely with how consistently doses are taken across the day rather than building toward one long-lasting peak.

Response varies by individual and by the underlying cause of spasticity, so a prescriber may reassess after a few weeks to decide whether the dose should be adjusted further, held steady, or, if benefit is insufficient despite reasonable titration, whether another approach should be considered.

Important Safety Priorities

Baclofen is generally well tolerated at appropriate doses, but a few safety points deserve particular attention. Drowsiness, dizziness, weakness, and fatigue are common, and people are cautioned about driving or operating machinery until they know how the medication affects them. Blood glucose elevations have been reported in some patients, so anyone managing diabetes may need closer glucose monitoring while adjusting to therapy. Baclofen should be used in pregnancy only if the potential benefit justifies the potential risk, since animal studies identified fetal effects and human data remain limited; it is also present in breast milk, so nursing parents should discuss the balance of benefits and risks with a healthcare provider.

Checklist Before Using Baclofen

Reviewing your health history against a checklist like this before the first dose, and again whenever your regimen changes, is a practical way to catch a relevant issue before it becomes a problem.

Interactions and Practical Precautions

Because Baclofen acts on the central nervous system, combining it with other substances that also cause sedation can intensify drowsiness, dizziness, or impaired coordination more than either substance alone. This is one of the more important practical precautions to plan around.

Substances That Commonly Warrant Caution

  • Alcohol, which can significantly increase sedation and impair coordination.
  • Other central nervous system depressants, including certain sleep aids, sedatives, and anxiety medications.
  • Opioid pain medications, which can compound drowsiness and increase the risk of slowed breathing.
  • Other muscle relaxants, since combining these agents may increase sedation, weakness, or other adverse effects and should be done only under professional supervision.
  • Medications that lower blood pressure, since Baclofen itself can occasionally contribute to lowered blood pressure.

Sharing a full list of current medications and relevant health conditions with a prescriber or pharmacist before starting Baclofen allows these interactions to be reviewed individually rather than guessed at.

Baclofen Compared With Other Muscle Relaxants

Because several muscle relaxants are used for overlapping types of spasticity or muscle tightness, understanding what genuinely differs between them is often more useful than a simple list of names. The comparisons below focus on mechanism, typical use pattern, and the kind of situation where each option tends to be favored.

Baclofen vs. Tizanidine

FeatureBaclofenTizanidine
Active ingredientBaclofenTizanidine
Pharmacologic classGABA-B receptor agonistCentrally acting alpha-2 adrenergic agonist
Primary indicationSpasticity from multiple sclerosis or spinal cord injuriesSpasticity from multiple sclerosis or spinal injury
Dosage formTabletTablet or capsule
Available strengths10 mg, 25 mg2 mg, 4 mg
Key considerationRequires gradual dosage titration; higher risk of muscle weaknessShort duration of action; higher risk of dry mouth and low blood pressure
Comparison of two central antispasticity agents

Both Baclofen and Tizanidine act centrally on the nervous system, but through different receptors: Baclofen through GABA-B receptors, Tizanidine through alpha-2 adrenergic receptors. Tizanidine has a shorter duration of action and carries a distinct interaction and liver-monitoring profile, particularly with certain antibiotics and antidepressants, while Baclofen's main practical trade-off is its own gradual titration and the need to avoid abrupt stopping. Neither is inherently superior; the choice often comes down to how a person tolerates sedation, blood pressure effects, and dosing frequency.

Baclofen vs. Dantrolene

FeatureBaclofenDantrolene
Active ingredientBaclofenDantrolene
Site of actionCentrally acting in spinal cord pathwaysDirectly acts on skeletal muscle fibers
Dosage formTabletCapsule
Available strengths10 mg, 25 mg25 mg, 50 mg, 100 mg
Clinical monitoringRequires gradual tapering to avoid withdrawal symptomsRequires routine liver function testing due to potential hepatotoxicity
Comparison of centrally acting vs. peripherally acting antispasticity medications

Dantrolene works at the muscle fiber itself rather than primarily in the central nervous system. Its peripheral mechanism avoids some centrally mediated effects, although drowsiness can still occur, and it carries its own liver-related monitoring requirements. Dantrolene may be considered when central adverse effects are a major concern, while Baclofen is an established oral option for spasticity tied to multiple sclerosis or spinal cord injury.

Baclofen vs. Diazepam

FeatureBaclofenDiazepam
Active ingredientBaclofenDiazepam
Pharmacologic classGABA-B receptor agonistBenzodiazepine (GABA-A modulator)
Dosage formTabletTablet
Available strengths10 mg, 25 mg2 mg, 5 mg, 10 mg
Regulatory & dependence profileNon-controlled; abrupt stopping can cause acute withdrawalSchedule IV controlled substance; risk of dependence, tolerance, and misuse
Comparison of antispasticity treatments across regulatory and therapeutic profiles

Diazepam is a benzodiazepine that works through a different GABA receptor subtype (GABA-A rather than GABA-B) and is classified as a controlled substance due to its dependence potential. Baclofen is not a controlled substance and carries a different withdrawal profile, though both medications require caution around abrupt discontinuation. Diazepam's stronger sedative and anti-anxiety properties can be useful in specific spasticity patterns but also raise different long-term dependence considerations than Baclofen.

If exploring alternatives feels useful, our Muscle Relaxants selection lists other options for reference alongside Baclofen.

Baclofen Access and Prescription Requirements in the United States

Baclofen, as an active ingredient, is authorized for human medicinal use in the United States, and oral Baclofen tablets are classified as prescription medication here. That prescription status is a fact about the dosage form itself, separate from any brand, strength, package size, or our product-specific process for accepting an order. Our support team, including a pharmacist, is available to clarify the ordering steps and any documentation that applies before you submit an order.

Ordering, Delivery, and Receiving Your Order

We have operated as an online pharmacy since 2008, under Ireland RX, and our customer support team is reachable 24/7 through email, live chat, or phone, with a pharmacist available to answer medication questions. When you place an order for Baclofen tablets with us, our team confirms the order details, prepares the exact strength and pack size you selected, and packs it for dispatch.

We price and process orders in US dollars, and once your order is packed, it moves into our shipping process for delivery. Because delivery timing can vary by destination and courier conditions, we treat any stated delivery window as an estimate rather than a guarantee, and our support channels remain available if you want an update on where your package stands after dispatch.

Deciding on Baclofen Tablets

Baclofen tablets suit someone who has spasticity related to multiple sclerosis or spinal cord injury, who is working with a prescriber on a gradual titration, and who is comfortable with a multiple-times-daily oral routine and the sedation that can come with it. If central adverse effects are a bigger concern than liver monitoring, an alternative like Dantrolene may be worth discussing with a prescriber; if dependence potential is the primary concern, Baclofen's non-controlled status may weigh in its favor compared with Diazepam. Whichever direction fits your situation, we offer the 10 mg and 25 mg tablets in the package sizes listed here, and our support team is available around the clock if you have questions before you order.

Medically reviewed by
Sarah Jenkins
Lead Pharmacy Editor
Updated September 10, 2026

Customer questions

Asked by Angela P, Jacksonville, United States

I'm in Jacksonville. Can I see whether Baclofen Tablets can be shipped to my ZIP code before I submit an order?

Answered by Support team

Yes. Enter your full Jacksonville delivery address and ZIP code at checkout to see the shipping options available for that destination before placing the order.

Product specifications

Active ingredientBaclofen
Drug classSkeletal muscle relaxant
Dosage formTablet
Available strengths10 mg, 25 mg
RouteOral
StorageStore at 68°F to 77°F; brief excursions permitted between 59°F and 86°F. Keep in a tightly closed, light-resistant container, away from moisture.
ATC codeM03BX01

Regulatory information

Approval StatusBaclofen is officially approved by the FDA for human medical use in the United States.
Prescription RequirementOral tablets containing baclofen are classified as prescription-only medication and require an order from a licensed healthcare provider.

More information