Trialodine (Trazodone) Tablets

Trialodine contains oral trazodone, a well-established antidepressant from the serotonin antagonist and reuptake inhibitor (SARI) class. In the United States, trazodone is approved for treating major depressive disorder in adults. Prescribers also use trazodone off-label, often at lower doses, for insomnia and sometimes anxiety symptoms, in part because of its sedating effects.

What Trialodine Treats and How It Works

Trazodone blocks 5-HT2 serotonin receptors and inhibits serotonin reuptake. It also blocks histamine H1 and alpha-1 adrenergic receptors, which contributes to drowsiness and orthostatic dizziness. Antidepressant treatment generally uses higher total daily doses than off-label sleep regimens, but the dose and schedule must be individualized by a prescriber.

Essential Facts

For depression, treatment usually starts around 150 mg per day in divided doses, with gradual increases every few days as tolerated up to a typical outpatient ceiling of 400 mg daily. When trazodone is prescribed off-label mainly to support sleep, doses are usually much lower, often in the 25 mg to 100 mg range taken in the evening. Taking trazodone shortly after a meal or light snack improves absorption and can reduce dizziness. Sedative effects may begin within about 30 to 60 minutes, while the full antidepressant benefit generally takes two to four weeks to develop.

Here is a quick snapshot of the core product details:

Common side effects include drowsiness, dizziness, dry mouth, and blurred vision. Trazodone must not be used with a monoamine oxidase inhibitor or within 14 days of stopping one, and it is contraindicated in anyone with a known hypersensitivity to trazodone or a tablet ingredient. It should be combined cautiously with alcohol, other CNS depressants, or additional serotonergic medications because of the risks of excessive sedation or serotonin syndrome. Priapism is a rare but medically urgent adverse effect that requires immediate attention. Store Trialodine tablets at 68°F to 77°F, with brief excursions between 59°F and 86°F permitted. Keep the container tightly closed and protect it from light and moisture.

Available Strengths and Package Sizes

We currently list Trialodine in 25 mg, 50 mg, and 100 mg tablets, each offered in several pill counts so the pack size can match a prescribed daily dose and treatment length. The table below shows every combination we stock:

Larger pack sizes generally offer better per-pill value for people on a stable, longer-term regimen, while smaller counts suit a new prescription or a dose that is still being adjusted.

Important Notes Before You Order

Trazodone tablets have prescription-only status in the United States, and our pharmacist-supported team is available 24/7 by email, online chat, and phone if you have questions about your order or prescription. Trazodone tablets are not approved for pediatric use and carry a boxed warning about increased suicidal thoughts and behavior in pediatric and young adult patients taking antidepressants, so close monitoring by a prescriber is important. Because reliable safety data in pregnancy are limited, use during pregnancy is an individualized decision between a patient and their prescriber. Caution is also advised during breastfeeding because trazodone passes into breast milk. Sedation and dizziness can impair driving or operating machinery; follow the prescribed schedule and avoid hazardous activities until you know how the medicine affects you. If you are also managing anxiety or sleep difficulties alongside depression, you may want to review other options in our AntiDepressants section while continuing to use the strength and regimen directed by your prescriber. Since we began serving US customers in 2008, we have focused on straightforward ordering and dependable dispatch for maintenance medications like this one.